Amedeo Caflisch originally studied theoretical physics at the ETH Zurich (1983-1986). He received his doctorate degree from the ETH under the supervision of professors Max Anliker and Peter Niederer at the Institute of Biomedical Engineering and Medical Informatics in 1991 (the thesis title was "Monte Carlo-docking of polypeptide chains"). Amedeo subsequently moved to the United States, specifically to the Boston area, to pursue a postdoctoral position in the laboratory of Martin Karplus (from 1992 to 1994) at Harvard's Department of Chemistry. Having deepened his interest in proteins, primarily in their folding and stability, and in ligand binding, especially from a pharmaceutical point of view, Amedeo then joined the Department of Biochemistry at UZH in 1995 as an Oberassistent (habilitation candidate) in the group of Andreas Plückthun. While quickly establishing an independent research program focused on proteins and their (mis)folding on the one side and the discovery or design of drug candidate molecules on the other side, he was made an assistant professor in computational sciences in 1996. The lab's continued success in both applied and methodological research ensured that Amedeo was promoted to Full Professor of Computational Structural Biology in 2001, and this is the position he still holds today.

Amedeo is married and has four children (born in 1992, 1993, 1996 and 2003). Aside from his family and work, he is enthusiastic about Italian opera and running.

To find out more about Amedeo and the lab's work, please consider the following pages:
Departmental Page at UZH
Google Scholar
Researchgate