Abeta fibril elongation: Docked states D1-D3

Submitted by Caflisch_ADM on Tue, 10/24/2017 - 15:39

Explanation: 

These are the three docked states, D1-D3, we used to understand the locking pathways and dynamics of Aβ1-42 fibrils based on the model from Riek's lab (2BEG, solution NMR). The three states were aligned according to the chains C, D, and E, which retained the template's structure throughout the simulations. They are contained as separate models (as in an NMR structure), and you can use the Jmol interface to display them separately or all at once.

Publication Link: 
Amyloid β fibril elongation by monomers involves disorder at the tip